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The AI sector experienced a landmark year in the U.S. and globally.

According to TechCrunch’s data, 2024 saw 49 startups secure funding rounds of $100 million or more; notably, three firms completed multiple “mega-rounds,” and seven achieved rounds of $1 billion or greater.

How will 2025 measure up? With the year drawing to a close, 2025 has already equaled 2024 in the number of companies securing funding rounds of $100 million or more. Additionally, there’s been a notable increase in companies achieving multiple funding rounds exceeding $100 million this year compared to the last.

Below is a comprehensive list of U.S. AI companies that have secured $100 million or more in funding during the current year:

November

• Anysphere, responsible for the popular vibe-coding platform Cursor, secured $2.3 billion in a funding round, pushing its valuation to $29.3 billion. This, their second funding event this year, was announced on November 13.

• Parallel, a developer of web infrastructure for AI agents, announced a $100 million Series A round on November 12. Index Ventures and Kleiner Perkins jointly led this investment.

• The healthcare AI agent startup Hippocratic AI completed a $126 million Series C round, valuing the company at $3.5 billion. This investment, their second this year, was announced on November 3 and spearheaded by Avenir Growth.

October

• Fireworks AI, a platform facilitating the development of AI applications with open-source models, announced a $250 million Series C round on October 28. This funding valued the company at $4 billion.

• Enterprise AI firm Uniphore achieved a $2.5 billion valuation following a $260 million Series F round announced on October 22. Investors in this round included Snowflake Ventures, Nvidia, Databricks Ventures, and AMD, alongside others.

• Voice AI company Sesame secured a $250 million Series B round, jointly led by Sequoia and Spark Capital. Announced on October 21, the funding also saw participation from SignalRank.

• Cambridge, Massachusetts-based OpenEvidence, known for its AI chatbot in medicine, completed its second funding round of 2025. This $200 million Series C round, announced on October 20, set the company’s valuation at $6 billion.

• Lila Sciences, aiming to develop a science superintelligence platform, revealed its second funding round of 2025 on October 14. The $350 million Series A round was jointly spearheaded by Braidwell and Collective Global.

• Reflection AI, a rival to DeepSeek, unveiled its second mega-round of the year on October 9. The $2 billion Series B round, led by Nvidia, valued the company at $8 billion.

• EvenUp, a firm developing AI solutions for personal injury law, announced a $150 million Series E round on October 7, valuing the company at over $2 billion. Bessemer led the round, with Lightspeed, Bain Capital, and SignalFire, among others, also participating.

September

• Periodic Labs, an initiative focused on creating an AI scientist, disclosed a $300 million seed round on September 30. Felicis and Andreessen Horowitz co-led this investment, with Nvidia, Lightspeed, and Khosla Ventures, among others, also contributing.

• AI infrastructure provider Cerebras Systems secured a substantial $1.1 billion Series G round, valuing the company at $8.1 billion. This funding, announced on September 30, was jointly led by Fidelity and Atreides Management.

• Modular disclosed a $250 million funding round on September 24. The US Innovative Technology Fund led this investment, with GV, Greylock, and General Catalyst, among others, contributing.

• Distyl AI, a developer of AI enterprise software, announced a $175 million Series B round on September 23. This funding round valued the startup at $1.8 billion and included investments from firms such as Khosla Ventures and Lightspeed.

• AI infrastructure startup Upscale AI secured a substantial $100 million seed round, co-led by Maverick Silicon and Mayfield. Announced on September 17, the round also drew investments from StepStone Group, Stanford University, and Qualcomm Ventures, among others.

• Groq, an AI inference technology company, completed a $750 million Series E round, valuing the company at nearly $6.9 billion. This funding, announced on September 17, was spearheaded by Disruptive.

• AI training startup Invisible Technologies reached a $2 billion valuation following a $100 million fundraise, announced on September 16. Vanara Capital led the investment, with Greycroft, Tallwoods Capital, and Freestyle Capital, among others, also contributing.

• Cognition AI, known for its vibe-coding agent Devin, secured a $400 million Series C round, announced on September 8. Founders Fund led this round, valuing the company at $10.2 billion.

• AI Infrastructure startup Baseten completed a $150 million Series D round, valuing the company at $2.1 billion. The September 5 investment was led by Bond, with contributions from CapitalG, IVP, and Spark Capital, among others.

• Bret Taylor’s customer service AI agent platform, Sierra, secured $350 million in a round led by Greenoaks Capital. This funding, announced on September 4, valued Sierra at over $10 billion.

• You.com, an AI-powered personalized search engine, completed a $100 million Series C round, with Cox Enterprises at the helm. The investment, announced on September 3, valued the company at $1.5 billion.

• AI research lab Anthropic secured its second funding round of 2025 in September. Anthropic revealed a $13 billion Series F round on September 2, valuing the company at $183 billion. Iconiq, Fidelity, and Lightspeed jointly led this significant investment.

August

• The healthcare and housing automation platform EliseAI completed a $250 million Series E round, valuing the startup at $2.2 billion. Andreessen Horowitz led this investment, which was publicly announced on August 20.
• AI research lab Decart secured $100 million, achieving a $3.1 billion valuation. The funding round, announced on August 7, saw participation from Sequoia Capital, Benchmark, and Zeev Ventures, among others.

July

• Generative media platform Fal completed a $125 million Series C round, led by Meritech Capital Partners. Announced on July 31, this round valued Fal at $1.5 billion and included investors such as Salesforce Ventures, Shopify Ventures, and Google AI Futures Fund.
• Ambience Healthcare, a five-year-old company developing an AI healthcare operating system, secured a $243 million Series C round, co-led by Oak HC/FT and Andreessen Horowitz. Kleiner Perkins, OpenAI Startup Fund, and Smash Capital were among the other participants.
• AI research lab Reka AI raised $110 million in a funding round that included Snowflake and Nvidia. Announced on July 22, this Series B round valued the company at $1 billion.
• Thinking Machines Lab, an AI research facility, verified that it secured $2 billion on July 15. Andreessen Horowitz led this substantial seed round, with contributions from Nvidia, Accel, and AMD, among others. The company is now valued at $12 billion.
• Cambridge, Massachusetts-based OpenEvidence, developing an AI-driven search tool for medical professionals, raised $210 million, reaching a $3.5 billion valuation. This Series B round, announced on July 15, was co-led by Kleiner Perkins and GV.
• Harmonic, a company creating a mathematical reasoning engine, secured a $100 million Series B round, with Kleiner Perkins at the forefront. Announced on July 10, this investment valued the company at $875 million.

June

• AI healthcare unicorn Abridge revealed it completed a $300 million Series E round, valuing the company at $5.3 billion. Andreessen Horowitz led the investment, with Khosla Ventures also participating. This marked the company’s second round in 2025.
• Harvey, a creator of AI tools for the legal sector, announced on June 23 that it secured its second $300 million funding round in 2025. This recent Series E round, co-led by Kleiner Perkins and Coatue, elevated the company’s valuation to $5 billion.
• Healthcare AI startup Tennr announced a $101 million Series C round, led by IVP, with contributions from Lightspeed Venture Partners, GV, and Andreessen Horowitz, among others. This funding values the company at $605 million.
• Enterprise search startup Glean continues to attract significant investment. On June 10, the company announced a $150 million Series F round, led by Wellington Management, with Sequoia, Lightspeed Venture Partners, and Kleiner Perkins, among others, also participating. Glean’s valuation now stands at $7.25 billion.
• Anysphere, the AI research lab responsible for the AI coding tool Cursor, completed a substantial $900 million Series C round, valuing the company at nearly $10 billion. Thrive Capital led this investment, with Andreessen Horowitz, Accel, and DST Global also contributing.

May

• AI data labeling startup Snorkel AI revealed a $100 million Series D round on May 29, establishing its valuation at $1.3 billion. Addition led the round, with Prosperity7 Ventures, Lightspeed Venture Partners, and Greylock also participating.
• LMArena, a widely used, community-powered benchmarking tool for AI models, secured a $100 million seed round, valuing the startup at $600 million. Announced on May 21, the round was jointly led by Andreessen Horowitz and UC Investments, with Lightspeed Venture Partners, Kleiner Perkins, and Felicis also contributing.
• Las Vegas-based AI infrastructure firm TensorWave disclosed a $100 million Series A round on May 14. Magnetar Capital and AMD Ventures co-led this investment, with Prosperity7 Ventures, Nexus Venture Partners, and Maverick Silicon also participating.

April

• SandboxAQ finalized a $450 million Series E round on April 4, setting the AI model company’s valuation at $5.7 billion. Investors in this round included Nvidia, Google, and Bridgewater Associates founder Ray Dalio, among others.
• Runway, known for developing AI models for media production, completed a $308 million Series D round, announced on April 3, valuing the company at $3 billion. General Atlantic led this investment, with SoftBank, Nvidia, and Fidelity also participating.

March

• AI giant OpenAI secured an unprecedented $40 billion funding round, valuing the startup at $300 billion. This round, concluded on March 31, was led by SoftBank, with Thrive Capital, Microsoft, and Coatue, among others, also investing.
• On March 25, Nexthop AI, an AI infrastructure firm, announced the completion of a Series A round led by Lightspeed Venture Partners. The $110 million funding also saw contributions from Kleiner Perkins, Battery Ventures, and Emergent Ventures, among others.
• Cambridge, Massachusetts-based Insilico Medicine secured $110 million for its generative AI drug discovery platform, as announced on March 13. This Series E round valued the company at $1 billion and was jointly led by Value Partners and Pudong Chuangtou.
• AI infrastructure company Celestial AI completed a $250 million Series C round, establishing its valuation at $2.5 billion. The March 11 investment was led by Fidelity, with Tiger Global, BlackRock, and Intel CEO Lip-Bu Tan, among others, participating.
• Lila Sciences secured a $200 million seed round to support its ambition of building a science superintelligence platform. Flagship Pioneering led the round. The Cambridge, Massachusetts-based firm also obtained funding from March Capital, General Catalyst, and ARK Venture Fund, among other investors.
• Brooklyn-based Reflection.Ai, focused on developing superintelligent autonomous systems, completed a $130 million Series A round, valuing the year-old company at $580 million. Lightspeed Venture Partners and CRV jointly led this investment.
• AI coding startup Turing, which collaborates with LLM companies, finalized a Series E round on March 7, setting its valuation at $2.2 billion. The $111 million investment was led by Khazanah Nasional, with WestBridge Capital, Gaingels, and Sozo Ventures, among others, also participating.
• AI defense tech startup Shield AI secured $240 million in a Series F round that concluded on March 6. L3Harris Technologies and Hanwha Aerospace co-led this investment, with Andreessen Horowitz and the US Innovative Technology Fund, among others, also contributing. The company’s valuation was set at $5.3 billion.
• AI research and large language model firm Anthropic completed a $3.5 billion Series E round, valuing the startup at $61.5 billion. Announced on March 3, this investment was led by Lightspeed, with Salesforce Ventures, Menlo Ventures, and General Catalyst, among others, also participating.

February

• Together AI, a developer of open-source generative AI and AI model development infrastructure, secured a $305 million Series B round, valuing the company at $3.3 billion. The February 20 investment was co-led by Prosperity7 and General Catalyst, with Salesforce Ventures, Nvidia, and Lux Capital, among others, also contributing.
• AI infrastructure firm Lambda completed a $480 million Series D round, announced on February 19. This funding valued the startup at nearly $2.5 billion and was co-led by SGW and Andra Capital, with Nvidia, G Squared, and ARK Invest, among others, also participating.
• Abridge, an AI platform for transcribing patient-clinician conversations, achieved a $2.75 billion valuation in a Series D round announced on February 17. The $250 million investment was co-led by IVP and Elad Gil, with Lightspeed, Redpoint, and Spark Capital also among the contributors.
• AI legal tech firm Eudia secured $105 million in a Series A round, led by General Catalyst. Floodgate, Defy Ventures, and Everywhere Ventures, along with other VC firms and numerous angel investors, also participated. The round concluded on February 13.
• AI hardware startup EnCharge AI completed a $100 million Series B round, which also closed on February 13. Tiger Global led this investment, with Scout Ventures, Samsung Ventures, and RTX Ventures, among others, participating. The Santa Clara-based company was established in 2022.
• AI legal tech firm Harvey secured a $300 million Series D round, valuing the three-year-old company at $3 billion. Sequoia led the round, announced on February 12, with OpenAI Startup Fund, Kleiner Perkins, Elad Gil, and other investors also contributing.

January

• Synthetic voice startup ElevenLabs completed a $180 million Series C round, valuing the company at over $3 billion. Announced on January 30, the round was jointly led by ICONIQ Growth and Andreessen Horowitz, with Sequoia, NEA, and Salesforce Ventures, among others, also participating.
• Hippocratic AI, a firm specializing in large language models for healthcare, announced a $141 million Series B round on January 9. This investment valued the company at over $1.6 billion and was led by Kleiner Perkins, with Andreessen Horowitz, Nvidia, and General Catalyst also contributing.

This article has been updated on April 23, June 18, August 27, and November 26 to incorporate additional deals.

This article has been revised to clarify that while Abridge was founded in Pittsburgh, it is not currently stated to be based there.