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US AI Startups Attract Substantial Funding Throughout 2025 and into Early 2026

The artificial intelligence sector began 2025 on a high note, demonstrating considerable momentum.

According to TechCrunch’s analysis, 2024 saw 49 startups secure funding rounds of $100 million or more, with three companies completing multiple “mega-rounds” and seven achieving rounds exceeding $1 billion.

This growth trajectory persisted into 2025. Although fewer individual companies closed rounds greater than $1 billion (with Anthropic notably securing two such rounds), a higher number of firms—eight in total—successfully completed multiple funding rounds throughout the year, surpassing the 2024 figure.

Looking ahead to 2026, initial indicators suggest continued strength: Elon Musk’s xAI disclosed a $20 billion Series E round, and Sam Altman’s brain-computer interface venture, Merge Labs, secured a $250 million seed round (led by OpenAI) within the first weeks of the year. While these early signs are promising, we remain vigilant to observe if this fundraising momentum will be sustained.

Below is a comprehensive list of U.S. AI companies that successfully raised $100 million or more in the past year:

Funding activities in December included:

  • Austin, Texas-based Mythic, specializing in power-efficient compute for AI, secured a $125 million venture round on December 17. DCVC led this round, with additional participation from SoftBank, NEA, and Linse Capital.
  • Chai Discovery, which develops AI models for biotech and drug discovery, revealed a $130 million Series B round on December 15, bringing its valuation to $1.2 billion. Oak HC/FT and General Catalyst co-led this investment.
  • Generative media platform Fal announced its third funding round of 2025 on December 9. This $140 million Series D round, led by Sequoia, increased the company’s valuation to over $4.5 billion.
  • Unconventional AI, a one-year-old startup focused on re-imagining computing foundations for the AI era, unveiled a substantial $475 million seed round on December 8. Led by Lightspeed Venture Partners and Andreessen Horowitz, this round valued the company at nearly $4.5 billion.
  • Boston-based 7AI, a developer of cybersecurity AI agents, secured a $130 million Series A round, announced December 4. Index Ventures spearheaded this round, with contributions from Greylock, Spark Capital, and CRV, among others.

November

  • All-in-one AI workspace platform Genspark revealed a $275 million Series B round on November 20, which valued the company at $1.25 billion. Investors included Emergence Capital Partners, SBI Investment, and LG Technology Ventures.
  • Luma AI, known for creating models for photo and video generation, raised $900 million in a Series C round, placing the startup’s valuation at $4 billion. Humain led the round, with participation from Andreessen Horowitz, AMD Ventures, and Amplify Partners.
  • Viral vibe-coding platform Cursor raised $2.3 billion in a funding round, announced on November 13, valuing the company at $29.3 billion. This marks the company’s second funding round this year.
  • Parallel, dedicated to building web infrastructure for AI agents, announced a $100 million Series A round on November 12, co-led by Index Ventures and Kleiner Perkins.
  • Healthcare AI agent startup Hippocratic AI secured a $126 million Series C round, valuing the company at $3.5 billion. Announced on November 3, and led by Avenir Growth, this was the company’s second round this year.

October

  • Fireworks AI, a platform enabling users to build AI applications with open source models, announced a $250 million Series C round on October 28, valuing the company at $4 billion.
  • Enterprise AI startup Uniphore achieved a valuation of $2.5 billion following a $260 million Series F round, announced October 22. Investors included Snowflake Ventures, Nvidia, Databricks Ventures, and AMD.
  • Sesame, a voice AI company, raised a $250 million Series B round on October 21, co-led by Sequoia and Spark Capital, with SignalRank also participating.
  • Cambridge, Massachusetts-based OpenEvidence, developers of an AI chatbot for the medical field, completed its second funding round of 2025. This $200 million Series C round, announced October 20, valued the company at $6 billion.
  • Lila Sciences, aspiring to build a science superintelligence platform, announced its second funding round of 2025 on October 14. The $350 million Series A round was co-led by Braidwell and Collective Global.
  • DeepSeek competitor Reflection AI announced its second mega-round of the year on October 9. This $2 billion Series B round, led by Nvidia, valued the company at $8 billion.
  • EvenUp, which develops AI for the personal injury legal field, announced a $150 million Series E round on October 7, valuing the company at over $2 billion. Bessemer led the round, with participation from Lightspeed, Bain Capital, and SignalFire.

September

  • Periodic Labs, dedicated to building an AI scientist, announced a $300 million seed round on September 30. Felicis and Andreessen Horowitz led the round, with participation from Nvidia, Lightspeed, and Khosla Ventures.
  • Cerebras Systems, an AI infrastructure company, raised a substantial $1.1 billion Series G round, announced September 30, valuing the company at $8.1 billion. Fidelity and Atreides Management co-led this round.
  • Modular announced a $250 million funding round on September 24. The US Innovative Technology Fund led the round, with GV, Greylock, and General Catalyst among the participants.
  • Distyl AI, which develops AI enterprise software, raised a $175 million Series B round, announced September 23. This round valued the startup at $1.8 billion and included investors such as Khosla Ventures and Lightspeed.
  • AI infrastructure startup Upscale AI secured a sizable $100 million seed round, co-led by Maverick Silicon and Mayfield. Announced September 17, the round also included StepStone Group, Stanford University, and Qualcomm Ventures.
  • Groq, an AI inference company, raised a $750 million Series D-3 round, announced September 17, valuing the company at nearly $6.9 billion. Disruptive led this round.
  • AI training startup Invisible Technologies was valued at $2 billion after a $100 million fundraise, announced September 16. Vanara Capital led the raise, with participation from Greycroft, Tallwoods Capital, and Freestyle Capital.
  • Cognition AI, the creator of the vibe-coding agent Devin, announced a $400 million Series C round on September 8. Founders Fund led the round, valuing the company at $10.2 billion.
  • AI Infrastructure startup Baseten raised a $150 million Series D round that valued the company at $2.1 billion. The September 5 round was led by Bond, with participation from CapitalG, IVP, and Spark Capital.
  • Bret Taylor’s customer service AI agent platform Sierra raised $350 million in a round led by Greenoaks Capital. This fundraise, announced September 4, valued Sierra at over $10 billion.
  • You.com, a personalized AI search engine, secured a $100 million Series C round led by Cox Enterprises. The round, announced September 3, valued the company at $1.5 billion.
  • AI research lab Anthropic raised its second round of 2025 in September. Anthropic announced a $13 billion Series F round on September 2, valuing the company at $183 billion. Iconiq, Fidelity, and Lightspeed led the round.

August

  • Healthcare and housing automation platform EliseAI raised $250 million in a Series E round that valued the startup at $2.2 billion. The round, which was announced on August 20, was led by Andreessen Horowitz.
  • Decart, an AI research lab, raised $100 million at a $3.1 billion valuation. The round included Sequoia Capital, Benchmark, and Zeev Ventures, among others, and was announced on August 7.

July

  • Generative media platform Fal raised a $125 million Series C round led by Meritech Capital Partners. The company announced the round, which values Fal at $1.5 billion, on July 31. Salesforce Ventures, Shopify Ventures, Google AI Futures Fund, and others joined the round.
  • Five-year-old Ambience Healthcare, which is building an AI healthcare operating system, raised a $243 million Series C round that was led by Oak HC/FT and Andreessen Horowitz. Kleiner Perkins, OpenAI Startup Fund, Smash Capital, and others also participated in the round.
  • Reka AI, an AI research lab, raised $110 million in a round that included Snowflake and Nvidia. The Series B round was announced on July 22 and values the company at $1 billion.
  • AI research lab Thinking Machines Lab confirmed that it raised $2 billion on July 15. This sizable seed round was led by Andreessen Horowitz with participation from Nvidia, Accel, and AMD, among others. The round values the company at $12 billion.
  • Cambridge, Massachusetts-based OpenEvidence, which is building an AI-powered search tool for clinicians, raised $210 million at a $3.5 billion valuation. The Series B round was announced on July 15 and was led by Kleiner Perkins and GV.
  • Harmonic, which is building a mathematical reasoning engine, raised a $100 million Series B round led by Kleiner Perkins. The round was announced on July 10 and values the company at $875 million.

June

  • Healthcare AI unicorn Abridge announced it raised a $300 million Series E round that values the company at $5.3 billion. The round was led by Andreessen Horowitz with Khosla Ventures participating. It was the company’s second round of 2025.
  • Harvey, which builds AI tools for the legal industry, announced it raised its second $300 million round of 2025 on June 23. This latest Series E round was co-led by Kleiner Perkins and Coatue and brings the company’s valuation to $5 billion.
  • Healthcare AI startup Tennr announced it raised a $101 million Series C round led by IVP with participation from Lightspeed Venture Partners, GV, and Andreessen Horowitz, among others. The round values the company at $605 million.
  • Enterprise search startup Glean continues to rake in cash. The company announced a $150 million Series F round on June 10, led by Wellington Management with participation from Sequoia, Lightspeed Venture Partners, and Kleiner Perkins, among others. Glean is now valued at $7.25 billion.
  • AI coding tool Cursor, raised a sizable $900 million Series C round that values the company at nearly $10 billion. The round was led by Thrive Capital with participation from Andreessen Horowitz, Accel, and DST Global.

May

  • AI data labeling startup Snorkel AI announced a $100 million Series D round on May 29, valuing the company at $1.3 billion. The round was led by Addition with participation from Prosperity7 Ventures, Lightspeed Venture Partners, and Greylock.
  • LMArena, a popular, community-driven benchmarking tool for AI models, raised a $100 million seed round that valued the startup at $600 million. The round was announced on May 21 and was co-led by Andreessen Horowitz and UC Investments. Lightspeed Venture Partners, Kleiner Perkins, and Felicis also participated, among others.
  • Las Vegas-based AI infrastructure company TensorWave announced a $100 million Series A round on May 14. The round was co-led by Magnetar Capital and AMD Ventures with participation from Prosperity7 Ventures, Nexus Venture Partners, and Maverick Silicon.

April

  • SandboxAQ closed a $450 million Series E round on April 4 that valued the AI model company at $5.7 billion. The round included Nvidia, Google, and Bridgewater Associates founder Ray Dalio among other investors.
  • Runway, which creates AI models for media production, raised a $308 million Series D round that was announced on April 3, valuing the company at $3 billion. It was led by General Atlantic. SoftBank, Nvidia, and Fidelity also participated.

March

  • AI behemoth OpenAI raised a record-breaking $40 billion funding round that valued the startup at $300 billion. This round, which closed on March 31, was led by SoftBank with participation from Thrive Capital, Microsoft, and Coatue, among others.
  • On March 25, Nexthop AI, an AI infrastructure company, announced that it had raised a Series A round led by Lightspeed Venture Partners. The $110 million round also included Kleiner Perkins, Battery Ventures, and Emergent Ventures, among others.
  • Cambridge Massachusetts-based Insilico Medicine raised $110 million for its generative AI-powered drug discovery platform as announced on March 13. This Series E round valued the company at $1 billion and was co-led by Value Partners and Pudong Chuangtou.
  • AI infrastructure company Celestial AI raised a $250 million Series C round that valued the company at $2.5 billion. The March 11 round was led by Fidelity with participation from Tiger Global, BlackRock, and Intel CEO Lip-Bu Tan, among others.
  • Lila Sciences raised a $200 million seed round as it looks to create a science superintelligence platform. The round was led by Flagship Pioneering. The Cambridge, Massachusetts-based company also received funding from March Capital, General Catalyst, and ARK Venture Fund, among others.
  • Brooklyn-based Reflection.Ai, which looks to build superintelligent autonomous systems, raised a $130 million Series A round that values the 1-year-old company at $580 million. The round was led by Lightspeed Venture Partners and CRV.
  • AI coding startup Turing closed a Series E round on March 7 that valued the startup, which partners with LLM companies, at $2.2 billion. The $111 million round was led by Khazanah Nasional with participation from WestBridge Capital, Gaingels, and Sozo Ventures, among others.
  • Shield AI, an AI defense tech startup, raised $240 million in a Series F round that closed on March 6. This round was co-led by L3Harris Technologies and Hanwha Aerospace, with participation from Andreessen Horowitz and the US Innovative Technology Fund, among others. The round valued the company at $5.3 billion
  • AI research and large language model company Anthropic raised $3.5 billion in a Series E round that valued the startup at $61.5 billion. The round was announced on March 3 and was led by Lightspeed with participation from Salesforce Ventures, Menlo Ventures, and General Catalyst, among others.

February

  • Together AI, which creates open source generative AI and AI model development infrastructure, raised a $305 million Series B round that valued the company at $3.3 billion. The February 20 round was co-led by Prosperity7 and General Catalyst with participation from Salesforce Ventures, Nvidia, Lux Capital, and others.
  • AI infrastructure company Lambda raised a $480 million Series D round that was announced on February 19. The round valued the startup at nearly $2.5 billion and was co-led by SGW and Andra Capital. Nvidia, G Squared, ARK Invest, and others also participated.
  • Abridge, an AI platform that transcribes patient-clinician conversations, was valued at $2.75 billion in a Series D round that was announced on February 17. The $250 million round was co-led by IVP and Elad Gil. Lightspeed, Redpoint, and Spark Capital also participated, among others.
  • Eudia, an AI legal tech company, raised $105 million in a Series A round led by General Catalyst. Floodgate, Defy Ventures, and Everywhere Ventures also participated in the round in addition to other VC firms and numerous angel investors. The round closed on February 13.
  • AI hardware startup EnCharge AI raised a $100 million Series B round that also closed on February 13. The round was led by Tiger Global with participation from Scout Ventures, Samsung Ventures, and RTX Ventures, among others. The Santa Clara-based business was founded in 2022.
  • AI legal tech company Harvey raised a $300 million Series D round that valued the 3-year-old company at $3 billion. The round was led by Sequoia and announced on February 12. OpenAI Startup Fund, Kleiner Perkins, Elad Gil, and others also participated in the raise.

January

  • Synthetic voice startup ElevenLabs raised a $180 million Series C round that valued the company at more than $3 billion. It was announced on January 30. The round was co-led by Iconiq and Andreessen Horowitz. Sequoia, NEA, Salesforce Ventures, and others also participated in the round.
  • Hippocratic AI, which develops large language models for the healthcare industry, announced a $141 million Series B round on January 9. This round valued the company at more than $1.6 billion and was led by Kleiner Perkins. Andreessen Horowitz, Nvidia, and General Catalyst also participated, among others.

This article has been updated multiple times, specifically on April 23, June 18, August 27, November 26, and January 19, 2026, to incorporate additional funding announcements.

An edit has been made to this article to clarify that Abridge was founded in Pittsburgh but is not necessarily still based there.

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